Performance highlights

Financials

Revenues and other operating income

Outlook for 2010

Use continued strong operating cash flow to accelerate product development.
Research & development spending to increase by over one-third, while maintaining a healthy operating profit.
Revenues and other operating income broadly in line with 2009.1
1
In guidance currency = EUR/USD rate of 1.41.

Selected financial data

Our consolidated financial statements and Company financial statements (hereinafter referred to as the ‘financial statements’), and the notes thereto, have been prepared in accordance with International Financial Reporting Standards (IFRS) as endorsed by the European Union (EU) and as issued by the International Accounting Standards Board (IASB). No differences resulted in our financial statements as a result of the preparation in accordance with IFRS as endorsed by the EU and IFRS as issued by IASB as applied to Crucell.

Prior to 2006, we prepared our financial statements, as included in Form 20-F, in accordance with accounting principles generally accepted in the US (US GAAP), which differs in certain significant respects from, and is not comparable with, IFRS. On December 21, 2007, the SEC approved rule amendments under which Form 20-F, as prepared by Foreign Private Issuers (FPIs), will no longer require reconciliation to US GAAP if the financial statements are prepared in accordance with IFRS as issued by the IASB. This rule is applicable for the 2008 financial year. As a result, we do not provide reconciliation to US GAAP.

The selected financial data should be read in conjunction with ‘Operating and financial review and prospects’ and our financial statements and accompanying notes thereto, included elsewhere in this Annual Report.

The following table shows the selected financial data under IFRS for the years ended December 31, 2005 through 2009.

IFRS selected financial data

Year ended December 31,
(in thousands of Euro, except share data)
2009 20081 20071 20061 20051
Consolidated statement of income data:
Revenues:
Product sales 304,439 226,055 177,569 103,918
License revenues 23,049 30,202 12,211 16,955 20,848
Service fees 10,675 10,900 14,006 10,694 11,881
Total revenues 338,163 267,157 203,786 131,567 32,729
 
Total cost of sales (194,613) (145,755) (134,884) (90,489) (7,156)
Gross margin2 143,550 121,402 68,902 41,078 25,573
Total other operating income 19,839 16,152 9,330 9,356 4,840
Operating expenses:
Research & development (70,176) (70,229) (63,995) (67,606) (34,048)
Selling, general and administrative (61,400) (64,778) (63,566) (47,478) (13,689)
Restructuring (3,120)
(Reversal of) impairment 7,199 4,888 (171) (30,416)
Total other operating expenses (124,377) (130,119) (127,732) (148,620) (47,737)
Operating profit/(loss) 39,012 7,435 (49,500) (98,186) (17,324)
Financial income & expenses (3,193) (2,662) 1,378 1,747 2,201
Results non-consolidated companies 2,147 1,442 1,190 (1,956) (455)
Disposal of subsidiaries (367)
Profit/(loss) before tax 37,966 5,848 (46,932) (98,395) (15,578)
Income tax (14,028) 8,402 2,598 10,611
Profit/(loss) for the year 23,938 14,250 (44,334) (87,784) (15,578)
 
Net profit/(loss) per share–basic 0.34 0.22 (0.68) (1.54) (0.39)
Net profit/(loss) per share–diluted 0.33 0.21 (0.68) (1.54) (0.39)
Weighted average shares outstanding–basic 70,266 65,593 65,103 57,064 39,852
 
Consolidated statement of financial position data:
Assets:
Cash and cash equivalents 327,837 170,969 163,248 157,837 111,734
Total current assets 655,071 322,318 303,262 317,071 131,038
Total assets 1,011,131 636,297 629,838 653,961 169,737
Liabilities and shareholders’ equity:
Total shareholders’ equity 738,265 452,534 440,913 497,683 137,609
Total non-current liabilities 114,700 65,462 74,183 66,026 9,380
Total current liabilities 158,166 118,301 114,742 90,252 22,748
Total liabilities and shareholders’ equity 1,011,131 636,297 629,838 653,961 169,737
Number of employees 1,248 1,126 1,126 1,073 282
1
Prior year numbers have been adjusted retrospectively, following the change in accounting policy to recognize actual gains and losses in other comprehensive income.
2
Gross margin = total revenues less cost of sales.

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